{"id":658625,"date":"2025-11-19T16:59:12","date_gmt":"2025-11-19T15:59:12","guid":{"rendered":"https:\/\/fermentis.com\/?post_type=product&#038;p=658625"},"modified":"2026-03-18T17:35:12","modified_gmt":"2026-03-18T16:35:12","slug":"safspirit-r-4","status":"publish","type":"product","link":"https:\/\/fermentis.com\/en\/product\/safspirit-r-4\/","title":{"rendered":"SafSpirit\u2122 R-4"},"content":{"rendered":"<div class=\"container section-title-container\" ><h2 class=\"section-title section-title-center\"><b aria-hidden=\"true\"><\/b><span class=\"section-title-main\" style=\"font-size:115%;\">A reliable yeast, especially in tough conditions such as low-grade sugar cane molasses<\/span><b aria-hidden=\"true\"><\/b><\/h2><\/div>\n<p>SafSpirit\u2122 R-4 is a reliable yeast strain designed to perform consistently well across a wide range of cane molasses. The quality of molasses can vary across countries, depending on various factors such as composition (mineral content, ash, unfermentable sugars, solids). Some yeast strains will struggle to ferment lower-quality molasses. In comparison to other strains, SafSpirit\u2122 R-4 shows its true potential in challenging conditions, and is able to produce high levels of ethanol even in molasses with several stress factors (high gravity, low pH, high temperatures). SafSpirit\u2122 R-4 generally produces neutral flavor profiles.<\/p>\n<p><strong>Ingredients:<\/strong> Yeast (<em>Saccharomyces cerevisiae<\/em>), emulsifier: sorbitan monostearate (E\/INS 491)<\/p>\n<p><strong>Fermentation of sugars: <\/strong>Monosaccharides (primarily glucose and fructose) and disaccharides (primarily sucrose).<\/p>\n\t<div id=\"gap-1040216720\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-1040216720 {\n  padding-top: 30px;\n}\n<\/style>\n\t<\/div>\n\t\n<div class=\"container section-title-container\" ><h3 class=\"section-title section-title-center\"><b aria-hidden=\"true\"><\/b><span class=\"section-title-main\" style=\"font-size:115%;\">SafSpirit\u2122 R-4<\/span><b aria-hidden=\"true\"><\/b><\/h3><\/div>\n\n\t\t<div class=\"tabbed-content\">\n\t\t\t\n\t\t\t<ul class=\"nav nav-tabs nav-uppercase nav-size-normal nav-left\" role=\"tablist\"><li id=\"tab-dosage-&amp;-usage\" class=\"tab active has-icon\" role=\"presentation\"><a href=\"#tab_dosage-&amp;-usage\" role=\"tab\" aria-selected=\"true\" aria-controls=\"tab_dosage-&amp;-usage\"><span>Dosage &amp; Usage<\/span><\/a><\/li>\n<li id=\"tab-trial\" class=\"tab has-icon\" role=\"presentation\"><a href=\"#tab_trial\" tabindex=\"-1\" role=\"tab\" aria-selected=\"false\" aria-controls=\"tab_trial\"><span>TRIAL<\/span><\/a><\/li>\n<li id=\"tab-typical-analysis\" class=\"tab has-icon\" role=\"presentation\"><a href=\"#tab_typical-analysis\" tabindex=\"-1\" role=\"tab\" aria-selected=\"false\" aria-controls=\"tab_typical-analysis\"><span>Typical analysis<\/span><\/a><\/li>\n<li id=\"tab-storage-&amp;-shelf-life\" class=\"tab has-icon\" role=\"presentation\"><a href=\"#tab_storage-&amp;-shelf-life\" tabindex=\"-1\" role=\"tab\" aria-selected=\"false\" aria-controls=\"tab_storage-&amp;-shelf-life\"><span>Storage &amp; shelf life<\/span><\/a><\/li><\/ul><div class=\"tab-panels\"><div id=\"tab_dosage-&amp;-usage\" class=\"panel active entry-content\" role=\"tabpanel\" aria-labelledby=\"tab-dosage-&amp;-usage\">\n<p><b><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Dosage \/ Temperature:<\/span><\/span><\/b><\/p>\n<p><strong><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">30-50 g\/hL* (0.04 \u2013 0.06 oz\/gal). Recommended range: 25\u00b0C\u201335\u00b0C (77\u00b0F\u201395\u00b0F).<br \/>\n<\/span><\/span><\/strong><em><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">* We recommend broad dosing ranges, but the distiller must adjust the dose according to the fermentation temperature, attenuation, and desired organoleptic profile. Given the impact of yeast on the quality of the final alcohol, we strongly advise users to conduct fermentation trials before using our products commercially.\u00a0<\/span><\/span><\/em><\/p>\n<p><strong>Pitching<\/strong>:<\/p>\n<p><strong>\u2460 Direct inoculation:<\/strong><br \/>\nSprinkle the active dry yeast directly onto the surface of the fermentation medium (must, wort, mash, juice, etc.) at or above the fermentation temperature. The yeast must be added progressively, ensuring complete coverage of the fermentation medium to avoid the formation of clumps as much as possible. Ideally, the yeast should be added while filling the first part of the vessel. It is possible to inoculate at temperatures above those selected for fermentation, providing that the temperature is then adjusted when the rest of the fermentation medium is added.<\/p>\n<p><strong>\u2461 With prior rehydration:<\/strong><br \/>\nAlternatively, sprinkle the yeast into 10 times the volume of fermentation media or water at 25\u00b0C\u201335\u00b0C (77\u00b0F\u201395\u00b0F). Leave to rest for 15 minutes, gently stir, then inoculate the resulting homogeneous cream into the fermenter.<\/p>\n<\/div>\n<div id=\"tab_trial\" class=\"panel entry-content\" role=\"tabpanel\" aria-labelledby=\"tab-trial\">\n<p>Fermentis research has shown that SafSpirit\u2122 R-4 is a strong and reliable solution for fermenting a large range of sugar cane molasses of variable qualities. SafSpirit\u2122 R-4 shows significantly better performance in stressful conditions compared to other yeast strains.<\/p>\n<div class=\"row\"  id=\"row-490039623\">\n\n\t<div id=\"col-1715170302\" class=\"col medium-6 small-12 large-6\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n\t<div class=\"img has-hover x md-x lg-x y md-y lg-y\" id=\"image_88229022\">\n\t\t\t\t\t\t\t\t<div class=\"img-inner dark\" >\n\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"443\" height=\"388\" src=\"https:\/\/fermentis.com\/wp-content\/uploads\/2025\/11\/SafSpirit-R-4_EN_V1-Fig.-1.avif\" class=\"attachment-large size-large not-transparent\" alt=\"\" data-has-transparency=\"false\" data-dominant-color=\"f8f7f6\" style=\"--dominant-color: #f8f7f6;\" \/>\t\t\t\t\t\t\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\n<style>\n#image_88229022 {\n  width: 100%;\n}\n<\/style>\n\t<\/div>\n\t\n<p class=\"thin-font\">Figure 1: Comparison of alcohol production by different yeast strains on easy to ferment sugar cane molasses.<\/p>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-1033012418\" class=\"col medium-6 small-12 large-6\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n\t<div class=\"img has-hover x md-x lg-x y md-y lg-y\" id=\"image_555143269\">\n\t\t\t\t\t\t\t\t<div class=\"img-inner dark\" >\n\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"441\" height=\"388\" src=\"https:\/\/fermentis.com\/wp-content\/uploads\/2025\/11\/SafSpirit-R-4_EN_V1-Fig.-2.avif\" class=\"attachment-large size-large not-transparent\" alt=\"\" data-has-transparency=\"false\" data-dominant-color=\"f8f7f6\" style=\"--dominant-color: #f8f7f6;\" \/>\t\t\t\t\t\t\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\n<style>\n#image_555143269 {\n  width: 100%;\n}\n<\/style>\n\t<\/div>\n\t\n<p class=\"thin-font\">Figure 2: Comparison of alcohol production by different yeast strains on difficult to ferment sugar cane molasses.<\/p>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n<\/div>\n<div class=\"row\"  id=\"row-1501013185\">\n\n\t<div id=\"col-1420275262\" class=\"col medium-8 small-12 large-8\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n\t<div class=\"img has-hover x md-x lg-x y md-y lg-y\" id=\"image_313522757\">\n\t\t\t\t\t\t\t\t<div class=\"img-inner dark\" >\n\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1013\" height=\"510\" src=\"https:\/\/fermentis.com\/wp-content\/uploads\/2025\/11\/SafSpirit-R-4_EN_V1-Fig.-3.avif\" class=\"attachment-large size-large not-transparent\" alt=\"\" srcset=\"https:\/\/fermentis.com\/wp-content\/uploads\/2025\/11\/SafSpirit-R-4_EN_V1-Fig.-3.avif 1013w, https:\/\/fermentis.com\/wp-content\/uploads\/2025\/11\/SafSpirit-R-4_EN_V1-Fig.-3-800x403.avif 800w, https:\/\/fermentis.com\/wp-content\/uploads\/2025\/11\/SafSpirit-R-4_EN_V1-Fig.-3-768x387.avif 768w, https:\/\/fermentis.com\/wp-content\/uploads\/2025\/11\/SafSpirit-R-4_EN_V1-Fig.-3-600x302.avif 600w\" sizes=\"auto, (max-width: 1013px) 100vw, 1013px\" data-has-transparency=\"false\" data-dominant-color=\"faf9f8\" style=\"--dominant-color: #faf9f8;\" \/>\t\t\t\t\t\t\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\n<style>\n#image_313522757 {\n  width: 100%;\n}\n<\/style>\n\t<\/div>\n\t\n<p class=\"thin-font\">Figure 3: Comparison of alcohol production of different yeast strains depending on the sugar concentration.<\/p>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-65810280\" class=\"col medium-4 small-12 large-4\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<p>Moreover, considering its good performance on stressful conditions with high sugar concentration, <strong>SafSpirit\u2122 R-4<\/strong> is a suitable solution to ferment sugar cane molasses at intermediate and high gravity.<br \/>\nThe performance has been measured at pH levels between 3.8 to 5.0.<\/p>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n<\/div>\n<\/div>\n<div id=\"tab_typical-analysis\" class=\"panel entry-content\" role=\"tabpanel\" aria-labelledby=\"tab-typical-analysis\">\n<p>% dry weight: 94.0-96.5%<br \/>\nViable cells: &gt; 15 x 10<sup>9<\/sup>CFU\/g<br \/>\nTotal bacteria: &lt; 1 CFU\/10<sup>7<\/sup> yeast cells<br \/>\nAcetic acid bacteria: &lt;1 CFU\/10<sup>8<\/sup> yeast cells<br \/>\nLactic acid bacteria: &lt;1 CFU\/10<sup>7<\/sup> yeast cells<br \/>\nPathogenic micro-organisms: in accordance with regulation<\/p>\n<\/div>\n<div id=\"tab_storage-&amp;-shelf-life\" class=\"panel entry-content\" role=\"tabpanel\" aria-labelledby=\"tab-storage-&amp;-shelf-life\">\n<p><b>PACKAGING:<br \/>\n<\/b>Cardboard box of 20 vacuum-packed sachets of 500g\/1.1 lb each (Full box net weight: 10 kg\/22.05 lb)<br \/>\nCardboard box of 1 vacuum-packed 10kg\/22.05 lb (Full box net weight: 10kg\/22.05 lb)<\/p>\n<p><b>STORAGE<\/b><\/p>\n<p>The product must be stored\/transported in dry conditions and protected from direct heat sources (e.g., sunlight, etc.).<br \/>\nThe product can be stored\/transported at ambient temperatures below 25\u00b0C\/77\u00b0F for up to 6 months without affecting its performance. Peaks up to 40\u00b0C\/104\u00b0F are allowed for a limited period (less than 5 days). For prolonged storage times (beyond 6 months) after the product has arrived at its final destination, Fermentis recommends storage at a controlled temperature (below 15\u00b0C\/59\u00b0F).<\/p>\n<p><b>SHELF LIFE<\/b><\/p>\n<p>36 months from the production date. Refer to the best-before end date printed on the sachet. Opened sachets must be sealed and stored at 4\u00b0C\/39\u00b0F and used within 7 days of opening. Do not use soft or damaged sachets.<\/p>\n<p><em>Each Fermentis yeast is developed under a specific production scheme and benefits from the know-how of the Lesaffre group, world leader in yeast manufacturing. This guarantees the highest microbiological purity and maximum fermentation activity.<\/em><\/p>\n<\/div><\/div><\/div>\n\t<div id=\"gap-1931603800\" class=\"gap-element clearfix\" style=\"display:block; height:auto;\">\n\t\t\n<style>\n#gap-1931603800 {\n  padding-top: 30px;\n}\n<\/style>\n\t<\/div>\n\t\n<p><em>The data contained in this technical sheet are the exact transcription of our knowledge of the product at the mentioned date. They are the exclusive property of Fermentis-Division of S.I.Lesaffre. It is of the user responsibility to make sure that the usage of this particular product complies with the legislation. Given the impact of yeast on the quality of the final alcool, we strongly advise users to make fermentation trials before any commercial usage of our products.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p><span data-olk-copy-source=\"MessageBody\">A reliable yeast, especially in tough conditions\u00a0such\u00a0as\u00a0low-grade\u00a0sugar\u00a0cane molasses<\/span><\/p>\n","protected":false},"featured_media":702751,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[221,220],"product_tag":[3118,3122],"class_list":{"0":"post-658625","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-active-dry-yeast-spirits","7":"product_cat-spirits-distilling","8":"product_tag-r-4","9":"product_tag-safspirit-r-4","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>SafSpirit\u2122 R-4 - The Versatile Yeast for Reliable Molasses Fermentation<\/title>\n<meta name=\"description\" content=\"Explore the reliable performance of SafSpirit\u2122 R-4, the yeast strain engineered by Fermentis to excel in cane molasses fermentation. 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Learn how this versatile strain can produce high ethanol yields even under challenging conditions like high gravity, low pH, and elevated temperatures. Discover the neutral flavor profile that makes SafSpirit\u2122 R-4 an ideal choice for consistent, high-quality spirit production.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/fermentis.com\/en\/product\/safspirit-r-4\/","og_locale":"en_US","og_type":"article","og_title":"SafSpirit\u2122 R-4","og_description":"Explore the reliable performance of SafSpirit\u2122 R-4, the yeast strain engineered by Fermentis to excel in cane molasses fermentation. Learn how this versatile strain can produce high ethanol yields even under challenging conditions like high gravity, low pH, and elevated temperatures. 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